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Ulcerative Colitis First Patient in Phase 2 Trial RPC1063

Home»News»News and Events»Ulcerative Colitis First Patient in Phase 2 Trial RPC1063»Ulcerative Colitis First Patient in Phase 2 Trial RPC1063

Receptos, Inc., announced today that its selective sphingosine‐1‐ phosphate 1 receptor (S1P1R) modulator, RPC1063, has been administered to the first patient in a Phase 2 study examining the and safety of induction therapy in patients with moderately to severely active (UC).

Leading to the initiation of the RPC01-202 study, called , Receptos successfully filed an Investigational New Drug (IND) Application with the Division of and Inborn Errors Products (DGIEP) of the Food and Drug Administration (USFDA). Receptos also has an active IND for RPC1063 with the Division of Neurology Products (DNP), under which an ongoing Phase 2/3 study for RPC1063 in Relapsing Multiple Sclerosis (RMS) is being enrolled.

TOUCHSTONE is a multi-national, multi-center, double-blind, randomized, placebo-controlled study investigating the effect of two active doses of RPC1063 versus placebo. The study is designed to enroll approximately 180 patients in , and Pacific. The primary objective of TOUCHSTONE is to compare the efficacy of RPC1063 for the induction of clinical in patients with moderately to severely active UC at eight weeks of treatment.

PR Newswire

Receptos Doses First Patient in Phase 2 Trial for RPC1063 in Ulcerative Colitis
PR Newswire (press release)
“RPC1063 not only has the potential to demonstrate efficacy in both induction and maintenance therapy for ulcerative colitis, but could represent a first-in-class offering for S1P1R modulation as a of action to treat and more »

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