Guidance on the role of new and established treatments for the management of ’s disease in adults and children has been published by The and Clinical Excellence (NICE).

Mainly affecting the (gut), Crohn’s disease is a that can develop at any age. However, it most commonly develops between the ages of 15 to 30, with approximately a third of patients diagnosed before 21 years old.

Marginally affecting more women than men, the cause is unknown, but is twice as likely to develop in smokers.

In the UK alone, there are presently around 115,000 people affected by the disease and between 3,000 to 6,000 new cases diagnosed every year.

Symptoms include recurring diarrhoea, and cramping (particularly after eating), blood and mucus in faeces, weight loss and . It can lead to infertility and a delay in puberty and growth in children.

There may be periods of time where symptoms are mild or non-existent, however flare-ups occur, where symptoms can become extreme.

Numerous drugs have been licensed for use in treating the condition over the last ten years.

or can be offered as maintenance treatment and glucocorticosteroids can be offered to encourage remission in people with Crohn’s disease.

The new guidance covers the use of these drugs in the care pathway for Crohn’s disease and is aimed at all healthcare professionals.

The guidance states to offer monotherapy with a conventional glucocorticosteroid (, methylprednisolone or intravenous ) to encourage remission in people with a first occurrence or a single inflammatory exacerbation of the illness in a 12 month period.

Also discuss with patients and their carer if suitable, their choices for managing it when they are in remission, including both no treatment and treatment.

The discussion should include the danger of inflammatory exacerbations, with and without drug treatment. Also talk about the possible side effects of drug treatment and record the person’s views in their notes.

Offer azathioprine or mercaptopurine as monotherapy to continue remission when formerly used with a conventional glucocorticosteroid or budesonide to induce remission.

Think about surgery as a substitute to medical treatment early in the course of the disease for patients whose disease is restricted to the distal ileum (small intestine).

Take into account the benefits and risks of medical treatment and surgery, the risk of recurrence after surgery and individual preferences and any personal or cultural considerations and record them in their notes.

Offer adults, children and young people, their parents or carers, age-appropriate multidisciplinary support.

This support should help them to handle any concerns about the disease and its treatment, including concerns about living with a chronic illness, body image and attending school.

“It is important that there are clear, evidence-based guidelines in place that can help improve the care offered to people with Crohn’s disease,” said Professor Mark Baker, director of the Centre for Clinical Practice at NICE.

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New guidelines on Crohn’s disease released by NICE
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Guidance on the role of new and established treatments for the management of Crohn’s disease in adults and children has been published by The National Institute for Health and Clinical Excellence (NICE). Mainly affecting the gastrointestinal tract (gut

About Rob Hill

In 1994, Rob was a fit, healthy 23-year-old, an amateur runner and athlete. Until that time, he had never really been sick. He didn’t even have a regular doctor. When the illness started, it progressed rapidly. Daily diarrhea. Sustained stomach cramps. The diagnosis was Crohn’s disease, an inflammatory condition of the digestive tract. It got worse, and his weight plummeted from 185 to 105 pounds. After a year and a half, it became clear that his large intestine, his colon, needed to be removed. Rob decided he had to do something about it. The Seven Summits campaign, which we call “No Guts Know Glory” grew from Rob’s love of sport, adventure and the outdoors. By taking it to the extreme, and on a global basis, Rob hopes to show people everywhere that having these diseases or having an ostomy, like Rob does, shouldn’t stop you from leading a full life. You may not be able to climb mountains, but there are so many other things you can do. To further this goal, Rob started the Intestinal Disease Education and Awareness Society (IDEAS), from his home base in Vancouver, British Columbia.

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