(INN, BAN), also known as mesalamine (USAN) or 5-aminosalicylic acid (5-ASA),
Working with your doctor to diagnose your symptoms is the first step in understanding and treating inflammatory bowel disease. However, some patients find their initial meeting with their doctor somewhat unsatisfactory because they do not have enough time to ask all the questions they may have. While most doctors do have busy schedules, you can make the most of your appointments with them by being well prepared.
Mesalazine is an anti-inflammatory drug used to treat inflammatory bowel disease, such as ulcerative colitis and mild-to-moderate Crohn’s disease. Mesalazine is a bowel-specific aminosalicylate drug that acts locally in the gut and has its predominant actions there, thereby having few systemic side effects.
- Exacerbation of the colitis
- Hypersensitivity reactions (including rash, urticaria aka hives, interstitial nephritis and lupus erythematosus-like syndrome)
- Hair loss
- Acute pancreatitis
- Nephrotic syndrome
- Blood disorders (including agranulocytosis, aplastic anaemia, leukopenia, neutropenia, thrombocytopenia)
Mesalazine avoids the sulfonamide side effects of sulfasalazine (which contains additional sulfapyridine), but carries additional rare risks of:
- Allergic lung reactions
- Allergic myocarditis