Genetic Links Found for Gastrointestinal Diseases

Genetic Links Found for Diseases – Harvard Crimson

A study published recently in Nature found new genetic links between Crohn’s disease and , two autoimmune gut diseases that affect as many as 1.4 million people in the United States. The research was an immense collaborative effort, combining 75,000 data samples from 80 institutions including the and Brigham and Women’s Hospital—both affiliated with —and the the Broad Institute.

“What this study shows is that by looking at genetic information for a large number of patients and controls you could map a genetic architecture of Crohn’s disease and colitis,” said , one of the study’s authors.“We used genome-wide association studies in combination with fine mapping tools … to identify genetic factors that either increase or decrease the risk for developing these diseases.”

Crohn’s disease and colitis, collectively referred to as inflammatory bowel disease (IBD), both involve inflammation of the . Colitis only affects the colon, while Crohn’s disease can affect any gastrointestinal area from the mouth to the anus.

Genetic Links Found for Gastrointestinal Diseases
Harvard Crimson
A study published recently in Nature found new genetic links between Crohn’s disease and ulcerative colitis, two autoimmune gut diseases that affect as many as 1.4 million people in the United States. The research was an immense collaborative effort,
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New S4M-04757 – Adverse Effects of Inflammatory Bowel Disease on the DeHavilland (press release) (subscription)all 8 news articles »

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