Ensemble on Track with Treatment

Small molecule therapeutics developer Ensemble Therapeutics reported positive preclinical data of its small molecule Interleukin-17 (IL-17) antogonist, which puts the company on track to nominate a drug candidate for clinical development in 2013.

The Cambridge-based company said its Ensemblins have strong oral activity as antagonists of IL-17, a cytokline shown in diseases such as psoriasis, , Crohn’s disease and . Ensemble Senior Vice President of Biology David Livingston presented the data during a presentation of its data at the annual meeting of the American College of Rheumatology (ACR) taking place in Washington, DC this week.

 

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Ensemble on track with autoimmune disease treatment
Mass High Tech
The Cambridge-based company said its Ensemblins have strong oral activity as antagonists of IL-17, a cytokline shown in diseases such as , rheumatoid arthritis, Crohn’s disease and inflammatory bowel disease. Ensemble Senior Vice President of
Ensemble Therapeutics Presents Oral Efficacy of First-in-Class Small Molecule MarketWatch (press release)all 6 news articles »

About Rob Hill

In 1994, Rob was a fit, healthy 23-year-old, an amateur runner and athlete. Until that time, he had never really been sick. He didn’t even have a regular doctor. When the illness started, it progressed rapidly. Daily diarrhea. Sustained stomach cramps. The diagnosis was Crohn’s disease, an inflammatory condition of the digestive tract. It got worse, and his weight plummeted from 185 to 105 pounds. After a year and a half, it became clear that his large intestine, his colon, needed to be removed. Rob decided he had to do something about it. The Seven Summits campaign, which we call “No Guts Know Glory” grew from Rob’s love of sport, adventure and the outdoors. By taking it to the extreme, and on a global basis, Rob hopes to show people everywhere that having these diseases or having an ostomy, like Rob does, shouldn’t stop you from leading a full life. You may not be able to climb mountains, but there are so many other things you can do. To further this goal, Rob started the Intestinal Disease Education and Awareness Society (IDEAS), from his home base in Vancouver, British Columbia.

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