Crohn’s Disease Linked To Enterovirus

Crohn’s Disease Linked To Enterovirus., Researchers have discovered that a cohort of children with Crohn’s disease also have a virus in their intestines, known as enterovirus.

This is the first time that a link has been discovered between the and , which are a genus of positive-sense single-stranded RNA viruses.

The finding was published in the international journal Clinical and Translational Gastroenterology.

One of the authors of the study, Alkwin Wanders, at Uppsala University and , believes that the results could help better understand the root causes of Crohn’s disease.

Not much is known about what causes Crohn’s disease; there have been over 140 gene mutations associated with condition. Most of the genes that have been identified play a role in .

Hence, there have been many theories suggesting that the condition could be caused by a lack of immune defense against various different pathogens, which would mean that Crohn’s disease is a result of both environmental and genetic factors.

Researchers at and Génome Québec Innovation Centre, along with scientists from other Canadian and Belgian institutions, discovered there are DNA variations in a gene that increase susceptibility to developing Crohn’s disease. Their finding was published in Nature Genetics.

Crohn’s diseases is characterized by of the , affecting different parts of the gut, from the mouth down to the anus. Symptoms include: severe , weight loss, strictures in the intestines and diarrhea.

The genes associated with the onset of the condition are vital for the immune defense against a certain type of RNA virus.

Crohn’s Disease Linked To Enterovirus

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