Crohns Disease History

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Crohns Disease History

Crohn's disease can cause abdominal pain, diarrhea, weight loss, anemia, and fatigue. Some people may be symptom free most of their lives, while others can have severe chronic symptoms that never go away.

, a disease within the substantial group of inflammatory digestive tract diseases (IBD), is known as Crohn’s disease after a famous gastroenterologist, Doctor. Burrill B. Crohn. Crohn’s disease in the beginning came to be referred to as a medical entity when it was described by Dr. Crohn, Dr. Leon Ginzburg, and Dr. Gordon D. Oppenheimer in 1932.

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The symptoms of Crohn’s disease are similar to the symptoms of . However, a number of additional symptoms, not typically experienced in , may be experienced in patients with Crohn’s disease. One problem that is very uncommon in , but may be seen in Crohn’s disease, is the occurrence of fistulas and abscesses around the anus and ulcers within the anal canal. The complications occur because of the tendency of Crohn’s disease to penetrate more deeply into the bowel lining.

The initial explanation of this ailment was previously expressed by the Italian physician Giovanni Battista Morgagni (1682-1771) in 1769, while he clinically diagnosed a young man having a chronic, debilitating disease and diarrhea.History of Crohns Disease

Consecutive cases ended up being described in 1898 by John Berg and by Polish surgeon Antoni Lesniowski in 1904. In 1913, Scottish physician T. Kennedy Dalziel, at the meeting of the British Medical Association, described nine cases in which the patients suffered from intestinal obstruction.

On close examination of the inflamed bowel, the transmural inflammation that is characteristic of the disease was clearly evident. Abdominal cramps, fever, diarrhea and weight loss were observed in most patients, particularly young adults, in the 1920s and 1930s. In 1923, surgeons at the Mt Sinai Hospital in New York identified 12 patients with similar symptoms. Dr. Burrill B. Crohn, in 1930, pointed out similar findings in two patients whom he was treating.

On May 13, 1932, Dr. Crohn and his colleagues, Oppenheimer and Ginzburg, presented a paper on ?Terminal Ileitis?, describing the features of Crohn?s disease to the . This was published later that year as a landmark article in the Journal of the with the title “Regional Ileitis: A Pathologic and Chronic Entity.” The JAMA article was published at a time when the medical community was interested in new findings.

The findings were given significant recognition, while the Dalziel article in the British Medical Journal of 1913 was not. It is by virtue of alphabetization rather than contribution that Crohn’s name appeared as the first author. This was the first time the condition was reported in a widely-read journal, and the disease came to be known as Crohn’s disease.

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