Ulcerative Colitis

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Janssen Biotech FDA approval Simponi Ulcerative Colitis

Janssen Biotech FDA approval Simponi Ulcerative Colitis Janssen Biotech has announced the FDA approval of Simponi (golimumab) to treat moderately to severely active ulcerative colitis (UC) in adult patients with corticosteroid dependence or an inadequate response to or failed to tolerate oral aminosalicylates, oral corticosteroids, azathioprine, or 6-mercaptopurine. The first and only subcutaneously administered anti-tumor […]

Ulcerative Colitis Low Undetected Colorectal Cancer Risk

Preoperative dysplasia among patients with ulcerative colitis undergoing colectomy was linked to a low risk for undetected synchronous colorectal cancer in a study presented at the American Society of Colon and Rectal Surgeons Annual Meeting in Phoenix. Researchers evaluated the medical records of 2,130 patients with ulcerative colitis (UC) who underwent proctocolectomy, restorative proctocolectomy or […]

Ulcerative Colitis Weekend Surgery Adds Complication Risk

Weekend hospitalization for ulcerative colitis is associated with an increased risk for postoperative complications, according to the findings of a large retrospective study. The weekend effect is the well-described phenomenon of worse outcomes for patients hospitalised on a weekend compared with a weekday,” the authors write. However, this effect may not exist across all healthcare […]

Fish Oil Attenuates Omega-6 Polyunsaturated Fatty Acid

Fish Oil Attenuates Omega-6 Polyunsaturated Fatty Acid-Induced Dysbiosis and Infectious Colitis but Impairs LPS Dephosphorylation Activity Causing Sepsis Abstract Clinically, excessive ω-6 polyunsaturated fatty acid (PUFA) and inadequate ω-3 PUFA have been associated with enhanced risks for developing ulcerative colitis. In rodent models, ω-3 PUFAs have been shown to either attenuate or exacerbate colitis in […]

Ulcerative Colitis Clinical Trial Immune Initiates Bertilimumab Phase II

Ulcerative Colitis Clinical Trial Immune Initiates Bertilimumab Phase II Immune Pharmaceuticals Ltd. (“Immune”), a privately held Israeli company, and EpiCept Corporation (Nasdaq OMX Stockholm Exchange and OTCQX: EPCT) announced today that Immune is initiating, following authorization from Israeli health authorities, a Phase II double-blind placebo controlled study with its lead drug, bertilimumab, in patients with […]

Ulcerative Colitis associated Cytomegalovirus Infection

A trigger role of cytomegalovirus (CMV) was shown in the development of ulcerative colitis (UC) in mice. Fifteen cases of synchronous onset of CMV colitis and UC have been reported in literature. A careful prospective and retrospective survey identified CMV colitis in newly diagnosed UC patients at 4.5% (3/65 cases) and 8.2% (5/61 cases), respectively. […]

Ulcerative Colitis Receives FDA Approval of UCERIS

Santarus Receives FDA Approval of UCERIS (Budesonide) for the Induction of …MarketWatch (press release)Santarus, Inc. (NASDAQ:SNTS) announced today that the U.S. Food and Drug Administration (FDA) has approved UCERIS(TM) (budesonide) extended release…

Crohn’s Disease and Ulcerative Colitis Beneficial Foods

Several Crohn’s Disease and Colitis affected individuals The differences between Crohn’s disease and ulcerative colitis, primary forms of inflammatory bowel disease (IBD), are hard to understand. Americans and Canadians with Crohn’s Disease and Ulcerative Colitis are looking for an alternative cure with probiotics bacteria products containing so-called “friendly” bacteria that populate the intestines.  Why? Researchers don’t yet know […]

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